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A biochemical oscillator to regulate the motor of tissue morphogenesis

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Tissue morphogenesis is driven by biomechanical forces generated by molecular motors such as myosin. Thanks to cell imaging, mathematical modeling and optogenetics, researchers at the Toulouse Center for Integrative Biology show that a biochemical oscillator controls the pulsatile contractility of myosin to regulate the lengthening of the ovarian follicle in Drosophila.
This study was published in Nature Communications on March 23rd, 2018.
The TRI platform of Genotoul participated to this study.